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Promethazine is used for relieving allergy symptoms, including hives or runny nose.

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Actavis promethazine over the counter drug used (but not sold) to treat ADHD. In 2005, The New England Journal of Medicine published a controversial study by researchers at the University of California, San Francisco, that showed patients who used promethazine had an increased risk of serious heart problems and cardiac arrests. In an editorial the BMJ, two leading experts on cardiac risks, Professors Michael F. Mann and James S. Siegel, cautioned the researchers, "The current study is likely to have important public health and clinical implications. It should be considered when making any recommendations for public health practice regarding the use of stimulant drugs in the treatment of ADHD." In 2006, a study by researchers at Children's Hospital and Medical Center in Philadelphia published by the medical quarterly New England Journal of Medicine and authored by researchers from the University of California, San Francisco and The University of California, San Francisco School Medicine found that a commonly used antihistamine drug, diphenhydramine, increases cardiovascular risks by increasing blood pressure. The researchers found a dose which is far below what would be normally recommended for short-term, acute use. "This would only increase cardiac risk if the drug was used for long periods, which is impossible to do without potentially dangerous side effects such as cardiovascular collapse … These findings further confirm that prescription drug interactions can have serious consequences." There are many medications that cause cardiac side effects, such as antihypertensive medications, aspirin and certain antidepressants. a major concern to the general public is not that the "right" drugs cause heart problems, but that there are so many drugs for conditions where a drug without cardiovascular side effects might be the logical choice. A 2008 study by researchers at the Harvard Medical School and Massachusetts Institute of Technology found that patients who take drugs on a daily basis and over the course of years and decades can have increased levels of cholesterol and triglycerides, possibly blood pressure. "This means that patients who were taking cholesterol-lowering drugs on a daily basis for 30 years have become saturated at their levels of lower cholesterol," write the Harvard Medical School and Massachusetts Institute of Technology researchers, "a finding that Bromocriptine buy online uk adds credence to the idea that drugs, as applied individually to individuals, can have unintended adverse effects on cardiovascular health." The researchers also suggest, though, that individuals who have certain genetic predispositions for risk are unlikely to be able protect their cardiovascular systems from the drugs they take, "suggesting a need to think about how individuals can best manage their risk of cardiovascular disease." A 2007 research review by scientists at the Johns Hopkins Bloomberg School of Public Health and the University of California, San Francisco found that there is no evidence stimulants alone prevent heart disease. The review, published in Circulation, examined 26 studies on heart disease which reported that people taking medications other than stimulants had more twice the odds of being diagnosed with heart disease than those who were not taking such medications. Another 2007 review for the American Heart Association found that although some drugs such as the medication fenfluramine have been Maxalt 10 mg coupon associated with a lower risk of certain fatal heart attacks, a careful reading of those studies found that overall, when the researchers excluded data on patients who were taking cardiovascular drugs and when only considering studies that included at least 2,000 patients, there were still no convincing.

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